會員登陸 / 下載中心
當前位置:產(chǎn)品目錄 > 抗體 >> 多克隆抗體
DNAI1 antibody, 軸絲中鏈動力蛋白抗體

 
編 號 PR-4564
產(chǎn)品名稱 DNAI1 antibody, 軸絲中鏈動力蛋白抗體
規(guī) 格 0.2ml
價 格 1980元
應(yīng) 用 WB,IHC,ELISA,ICC,IP,IF
品 牌 Hopebiot

詳細信息: 說明書下載

Background:  Involvement in disease: Defects in DNAI1 are the cause of primary ciliary dyskinesia type 1 (CILD1) . CILD1 is an autosomal recessive disorder characterized by axonemal abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit situs inversus, due to dysfunction of monocilia at the embryonic node and randomization of left-right body asymmetry. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome. Defects in DNAI1 are the cause of Kartagener syndrome (KTGS) [MIM:244400]. KTGS is an autosomal recessive disorder characterized by the association of primary ciliary dyskinesia with situs inversus. Clinical features include recurrent respiratory infections, bronchiectasis, infertility, and lateral transposition of the viscera of the thorax and abdomen. The situs inversus is most often total, although it can be partial in some cases (isolated dextrocardia or isolated transposition of abdominal viscera).

Description: Rabbit polyclonal to DNAI1

Immunogen: KLH conjugated synthetic peptide derived from DNAI1

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 73 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.

相關(guān)同類產(chǎn)品:

網(wǎng)站首頁 | 公司動態(tài) | 產(chǎn)品中心 | 定制服務(wù) | 代理產(chǎn)品 | 技術(shù)專欄 | 客戶留言 | 聯(lián)系我們

Copyright @ 2011 All Rights Reserved 江蘇鎮(zhèn)江厚普生物科技有限公司 備案/許可證編號為:蘇ICP備11043267號

地址:江蘇省丹陽市呂城工業(yè)園 郵編:212300 電子郵箱:hopebiotech@163.com

訂貨電話:0511-86909515 傳真:0511-86909515 訪問量:20333918