Background:  Nanos3, also known as Nos3 or NANOS1L, is a 173 amino acid protein that contains one nanos-type zinc finger, a structure composed of two C2HC domains that bind zinc and are required for Nanos3 function. Via its zinc finger, Nanos3 is involved in the maintenance of proximal germ cells, specifically by controlling germ cell proliferation and regulating the translation of specific mRNAs. The gene encoding Nanos3 maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).

Description: Rabbit polyclonal to Nanos3

Immunogen: KLH conjugated synthetic peptide derived from Nanos3

Specificity:  ·Reacts with Human, Mouse, Pig, Dog and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 151 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.