Background:  CD15 recognizes an antigen present on myelomonocytic cells and Lacto-Nfucopentose III (also known as hapten X). It is present on greater than 90% of granulocytes including neutrophils and eosinophils, and to a lesser degree, on monocytes. CD15 is expressed in Reed-Sternberg cells of Hodgkin’s disease (of the nodular sclerosis, mixed cellularity and lymphocyte-depleted subtypes), and certain types of epithelial cells. It is generally agreed that the Reed-Sternberg cell variants in lymphocyte-predominant Hodgkin’s disease are not reactive with CD15.

Description: Mouse monoclonal to CD15

Immunogen: KLH conjugated synthetic peptide derived from CD15

Specificity:  ·Recognizes Human CD15 in Immunohistochemiscal staining.

·Isotype: IgG

Application:  ·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Optimal working dilutions must be determined by the end user.