Background: MESP1, also known as bHLHc5, is a 268 amino acid protein that contains one basic helix-loop-helix (bHLH) domain, a motif that mediates protein dimerization and can bind to the E-box sequence of DNA. Localized to the nucleus, MESP1 functions as a transcription factor that, via its bHLH domain, participates in the epithelialization and the development of the cardiac and somitic mesoderm. Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways.

Description: Rabbit polyclonal to MESP1

Immunogen: KLH conjugated synthetic peptide derived from MESP1

Specificity:  ·Reacts with Human, Mouse, Pig, Dog and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 29 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.