Background: The homeodomain-interacting protein kinase (HIPK) family includes three members, HIPK1, HIPK2, and HIPK3. Each family member contains a conserved protein kinase domain as well as a separate domain, which interacts with homeoproteins. HIPK2 appears to act as a corepressor of homeodomain transcription factors, such as NK-3. Also, HIPK2 is regulated by ubiquitin-like modification via the covalent binding of SUMO-1. Subsequently, it is directed to nuclear bodies in vitro.
Description: Rabbit polyclonal to HIPK3
Immunogen: KLH conjugated synthetic peptide derived from HIPK3
Specificity: ·Reacts with Human, Mouse, Dog and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 134 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.