Background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic α/β horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. NOD9, also known as NLRX1, NOD26 or NOD5, is a 975 amino acid outer mitochondrial membrane protein that contains one NACHT domain and four LRR repeats. Expressed at high levels in heart, muscle and mammary gland, NOD9 plays a role in antiviral signaling, specifically via inhibition of virus-induced helicases, thereby acting as a negative regulator of antiviral responses.

Description: Rabbit polyclonal to NOD26

Immunogen: KLH conjugated synthetic peptide derived from NOD26

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 108 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.