Background: ARG1 (Arginase I), which is expressed almost exclusively in the liver, catalyzes the conversion of arginine to ornithine and urea. The human ARG1 gene, which maps to chromosome 6q23, encodes a 322 amino acid protein. ARG1 exists as a homotrimeric protein and contains a binuclear manganese cluster. ARG2 (Arginase II) catalyzes the same reaction as ARG1, but differs in its tissue specificity and subcellular location. Specifically, ARG2 localizes to the mitochondria. ARG2 is expressed in non-hepatic tissues, with the highest levels of expression in the kidneys, but, unlike ARG1, is not expressed in liver.

Description: Rabbit polyclonal to ARG1

Immunogen: KLH conjugated synthetic peptide derived from ARG1

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 35 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.