Background:  P2Y1 belongs to the family of G-protein coupled receptors, and functions as a receptor for extracellular ATP and ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. P2Y1 has been reported to be expressed in tissues throughout the body, particularly brain.

Description: Rabbit polyclonal to P2Y1

Immunogen: KLH conjugated synthetic peptide derived from P2Y1

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 40 kDa;

·Immunohistochemistry (Frozen/paraffin tissue section): 1/50-200;

·Immunocytochemistry: 1/100;

·ELISA: 1/500;

· Optimal working dilutions must be determined by the end user.