Background: The CXCR5 gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. CXCR5 protein is predicted to be a seven transmembrane G protein coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of the gene and its mouse conterpart strongly suggest the essential function of the protein is in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen.
Description: Rabbit polyclonal to CXCR5
Immunogen: KLH conjugated synthetic peptide derived from CXCR5
Specificity: ·Reacts with Human, Mouse, Rabbit, Pig, Cow and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 42 kDa;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;
·Immunocytochemistry: 1/200;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.