Background:  ABCB5 is a plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. ABCB5 is also responsible for the resistance to doxorubicin of a subset of malignant melanomas. ABCB5 has more recently been identified as a marker for human malignant-melanoma-initiating cells.

Description: Rabbit polyclonal to ABCB5

Immunogen: KLH conjugated synthetic peptide derived from ABCB5

Specificity:  ·Reacts with Human, Mouse, Dog, Cow and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/200-1000. Predicted Mol wt: 138 kDa;

·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;

·Immunocytochemistry: 1/100-500;

·ELISA: 1/1000;

·Optimal working dilutions must be determined by the end user.