Background:  CDK11 (Cyclin-dependent kinase 11) also known as cell division cycle 2-like 2 (CDC2L2) is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. This protein is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. The CDK11(p110/p58) kinases are essential for cellular viability as well as normal early embryonic development.

Description: Rabbit polyclonal to CDK11

Immunogen: KLH conjugated synthetic peptide derived from CDK11

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/200-1000. Predicted Mol wt: 90 kDa;

·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;

·Immunocytochemistry: 1/100-500;

·ELISA: 1/1000;

·Optimal working dilutions must be determined by the end user.