Catalog Number: PR-1358

Background:  CREB binding protein (CREBBP) is a nuclear protein that acetylates histones (giving a specific tag for transcriptional activation) and non-histone proteins (e.g., NCOA3 coactivator). CREBBP binds specifically to phosphorilated CREB, enhancing its transcriptional activity towards cAMP-responsive genes. This protein has also been reported to play a role in host-virus interactions: it binds HIV1 Tat (through KIX domain) and HTLV-1 tax and p30II.

Description: Rabbit polyclonal to CBP

Immunogen: KLH conjugated synthetic peptide derived from CBP

Specificity:  ·Reacts with Human, Mouse, Chicken, Dog and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 270 kDa;

·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;

·Immunocytochemistry: 1/100-500;

·ELISA: 1/500;

· Optimal working dilutions must be determined by the end user.