Background:  S3-12 (Adipocyte protein S3-12), also known as PLIN4 (Perilipin-4), is a 1,357 amino acid protein that belongs to the perilipin family. S3-12 contains a repeated 33–amino acid motif also found in adipophilin, and it shares protein sequence identity to both adipophilin and TIP-47 in the COOH terminus, but not to perilipin. S3-12 exhibits sequence similarity to the PAT proteins. Up-regulated during adipocyte differentiation, S3-12 may play a role in triacylglycerol packaging into adipocytes, and functions as a coat protein involved in the biogenesis of lipid storage droplets. S3-12 demonstrates highest expression in skeletal muscle, followed by heart and liver, and lowest expression in adult whole brain. Existing as two alternatively spliced isoforms, the S3-12 gene is conserved in dog, cow and mouse, and maps to human chromosome 19p13.3.

Description: Rabbit polyclonal to KIAA1881

Immunogen: KLH conjugated synthetic peptide derived from KIAA1881

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 134 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry: 1/100;

·Immunofluorescence: 1/50-200;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.