Background: SPLUNC2 (short palate, lung and nasal epithelium carcinoma-associated protein 2), also known as PSP or C20orf70, is a 249 amino acid protein belonging to the plunc family. SPLUNC2 is a secreted protein that has been found in the submandibular gland. The gene that encodes SPLUNC2 maps to human chromosome 20, which comprises approximately 2% of the human genome. Chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.
Description: Rabbit polyclonal to C20orf70
Immunogen: KLH conjugated synthetic peptide derived from C20orf70
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 27 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.