bNOS (nitric oxide synthase from brain) produces nitric oxide which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter. bNOS is an inhibitory transmitter for non-adrenergic and non cholinergic nerves in the colorectum. NOS is classified under three types: Type I NOS is found in neurons and is constitutively expressed and Ca2+/calmodulin dependent. It is called NOS-1, neuronal NOS (nNOS), brain NOS (bNOS), cerebral / constitutive / Ca2+ regulated NOS (cNOS). bNOS is present in skeletal muscles and its absence in Duchenne’s muscular dystrophy accounts for its symptoms of the disease. Type II NOS is 130kDa protein known as macrophage NOS (mNOS) or inducible NOS (iNOS). It is Ca2+/calmodulin independent and is expressed in activated macrophages and stimulated glial cells. Type III NOS is a 135kDa protein called endothelial NOS (eNOS).

一氧化氮合成酶-1催化生物體內(nèi)一氧化氮（NO）生成的酶。分神經(jīng)型一氧化氮合成的酶（nNOS or NOS1）、誘導(dǎo)型一氧化氮合成的酶（iNOS or NOS2）、內(nèi)皮型一氧化氮合成的酶（eNOS or NOS3）。此抗體識別分子量為150kDa的神經(jīng)型一氧化氮合成的酶。

我公司新研發(fā)的NOS1(氧化一氮合成酶)抗體已經(jīng)通過檢驗測試，可以應(yīng)用于蛋白印跡（WB），免疫組化（IHC），免疫細(xì)胞化學(xué)（ICC），酶聯(lián)免疫吸附試驗（ELISA），免疫沉淀（IP），免疫熒光（IF）實驗。具體信息如下：

編號           產(chǎn)品名稱

PR-1026，     NOS1 Antibody

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鎮(zhèn)江厚普生物科技有限公司銷售部

2015-10-28